As a minimum, annual vaccinations for CD&T (Clostridium C&D and tetanus) are required. Your veterinarian may recommend 7-way or 8-way vaccines, depending on the incidence of other diseases in your locale. Rabies vaccine may also be administered if rabies is endemic in your area, as llamas have contracted rabies. The level effectiveness of the rabies vaccine is still in question, however.
Many vaccines are not safe to give within 60 to 90 days after breeding or before birthing. Consult with your veterinarian for safe scheduling of all medications.